by Biotech Express Bureau
Gagandeep Kang FNA, FASc, FRS (born November 3, 1962) is a clinician scientist, Professor in the Department of Gastrointestinal Sciences at the Christian Medical College, Vellore, India and currently the executive director of the Translational Health Science and Technology Institute (THSTI), Faridabad, India.
Prof. Kang’s groundbreaking work has been recognized with numerous awards and honors. These include Woman Bioscientist of the Year from the Government of India (2006); election to Fellowship of the American Academy of Microbiology (2010), the Indian Academy of Sciences (2011), National Academy of Sciences (2013), the Faculty of Public Health in the UK (2015), and the Indian National Science Academy (2016).
Prof. Kang has made pivotal contributions to understanding the natural history of rotavirus infections as well as other enteric infections which are important causes of mortality and morbidity in India. Her work, often published in high-profile medical journals, has shown that natural immunity to rotavirus infections is much lower in the Indian population than in other populations. These findings lead directly to an understanding of why the rotavirus vaccine is not as efficacious in India as in other populations globally with similar socioeconomic demographics.
In collaboration with colleagues at CMC, Vellore, Kang has shown that the recipient may mount weaker enteric immunity to polio virus as well, providing an explanation for why Indians require more vaccinations with the oral polio vaccine for effective immunity. These findings raise the question of why both natural and vaccine-induced immunity to enteric viruses are weaker in India.
In addition to her basic research, Prof. Kang has extended her work to important practical areas. She has established a clinical laboratory for rotavirus vaccine evaluation that has provided critical reagents and training to rotavirus vaccine manufacturers not only in India but also in China and Brazil. She has been part of a collaborative network that developed an indigenous rotavirus vaccine for India starting with an Indian rotavirus isolate.
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